Biological age testing from one at-home blood spot: your pace of aging, eleven organ systems scored separately, and 105+ epigenetic biomarkers, read with you by a clinician, then a plan to improve how you are aging and a retest to prove it. You are not trying to live forever. You are trying to live better for longer.
Book a Free Consultation How it works ↓
100+ five-star reviewsClinician-ledTelehealthHSA/FSA acceptedAt HFW Longevity, we use advanced diagnostics, biological age testing, organ-system data, functional medicine, hormone optimization, peptide therapy, bioregulators, and quarterly biomarker tracking to help you understand how your body is aging — then build a clinician-guided plan to improve your health trajectory over time.
Led by Our Team of Advanced Care Clinicians
100% Telehealth
Testing Nationwide
HSA/FSA Accepted
24 pages on advanced testing, clinician-led protocols, and why strategy comes before any single compound.
Standard labs may miss:
You want to age better, but you do not want to guess.
You are not trying to live forever. You are trying to live better for longer.
You want to age better, and you do not want to guess.
One test tells you where you are. It cannot tell you which way you are heading. Two people can start from an identical result and be moving in opposite directions, and a single test cannot separate them. That is the whole argument for measuring more than once.
Biological age testing is useful and routinely oversold. How accurate is it? Accurate enough to be a reference point and, when repeated, a trend; not precise enough to be treated as a verdict. It can prompt better questions when a result does not match how you feel. It cannot prove that aging has been reversed, predict how long you will live, or prove what caused a change. HFW treats it as one input among several, read alongside your symptoms, history, conventional bloodwork, and goals.
Almost everyone starts with testing, from $500.
No membership to join first, and nothing to commit to beyond the test itself. The introductory call is free and works out which one fits.
Baseline versus trajectory
This is the whole argument for measuring more than once. Two people can start from an identical result and be moving in opposite directions. A single test cannot separate them, and neither can a plan built on one.
Both people had this exact result. On this information alone they look identical, and any plan built here is a guess about what happens next.
Illustrative only. No units, values or specific markers are shown. This is not a result for any patient, and it is not a prediction of what any individual plan will achieve. Direction can move either way, which is the reason to keep measuring.
Reading the number honestly
Biological age testing is genuinely useful and it is also routinely oversold. Being clear about both halves is part of how HFW uses it, and it is the difference between a number that informs a plan and a number that just sells one.
What it can do
What it cannot do
Biological age estimates are directional. HFW treats them as one input among several, interpreted alongside your symptoms, history, conventional bloodwork and goals.
The HFW difference
Conventional preventive care is essential and HFW does not replace it. These are the places where a longevity-focused approach asks a different question.
Age, family history, basic labs, and disease screening
Biological age, pace of aging, organ-system health, gut, hormones, metabolism, inflammation, mitochondria, nutrients, immune function, and recovery
“Everything looks normal.”
“Normal is not the same as optimized. Let’s look at how your body is aging.”
Standard bloodwork and population ranges
TruAge + TruHealth, comprehensive bloodwork, GI-MAP, DUTCH, Metabolomix+, NAD+, OAT, genetics, and custom panels when appropriate
General advice, medication, or watchful waiting
Correcting underlying contributors plus targeted longevity therapies when clinically appropriate
Annual visits or reactive follow-up
Quarterly labs, regular reviews, trend analysis, biological age tracking, and protocol adjustments
Avoid disease range
Improve function, resilience, recovery, healthspan, and biological aging patterns
Office visits, referrals, long waits
100% telehealth with at-home and local testing options
DNA methylation is a chemical tag your cells add to DNA to switch genes on and off. The pattern shifts with age, environment, and behavior, which is what makes it measurable, and why measuring it more than once tells you something a single genetic test never can.
Trained against chronological age. These produce your intrinsic age, which reads the cells themselves, and your extrinsic age, which includes immune cell shifts. Where the two diverge is itself informative, and the higher of the two is the one worth prioritizing.
Trained against aging phenotypes rather than the calendar, so they track health outcomes more closely than age alone. This is where methylation-based telomere length sits.
Measures rate rather than accumulated state, answering whether you are currently aging faster or slower than one year per year. It is the output most likely to move first, often within three months of a real change in what you do. Overall biological age is slower, usually six months or more.
The same methylation data produces system-level estimates, which is how the report indicates that one system looks more strained than another. A single whole-body age is interesting. Knowing which systems appear to need support first is what shapes the plan. Collection is a blood spot kit you complete at home. No lab visit is required.
TruAge and TruHealth give a read on each foundation from a single blood spot, and organ-system scoring shows which are under the most strain.
Often the answer is no new intervention at all. A stable finding is a reason to re-measure in six months, not to add something to your plan.
24 pages on advanced testing, clinician-led protocols, and why strategy comes before any single compound.
Real progress. Real support. No shame.
Stella Blanch Apo
It’s been a blessing working with Dr. Landi and his entire team! After getting my test results, Dr. Landi walked me through a number of helpful steps to restore my health. He is very knowledgeable and uses an in-depth functional medicine approach in addressing health concerns. Bernadette is also very kind and thoughtful and I enjoy the interpersonal connection I have built with all of them.
Chase Natale
Fatimah Fahmy
I have been working with Dr Landi for several months now. He is extremely knowledgeable, attentive and responsive. He actually listens which is rare in medicine these days. I’m excited to see what the results are from my protocol in a couple of months. Highly recommend his practice if you’re looking into functional medicine.
Lauren Griffith
Dr. Landi is highly knowledgeable and skilled in the field of functional medicine, but he also possesses a genuine empathy and compassion that is so often lacking in the traditional healthcare system. Dr. Landi connects to each of his patients on a personal level, works with you every step of the way, and makes you feel supported while navigating challenging health obstacles.
Kevin Heckman
I found out about the practice of Functional Dr’e last year and realized this is what I need! Finding Dr Landi so close to home was awesome. We appreciated his candor, knowledge and engaging personality. He exuded caring and interest in me and my situation. I feel he had repeatedly gone the extra mile for me so our collaboration is successful.
How the measurement works
DNA methylation is a chemical tag your cells add to DNA to switch genes on and off. The pattern shifts with age, environment and behavior, without altering the underlying sequence. That is what makes it measurable, and it is why measuring it more than once tells you something a single genetic test never can.
First generation
How old does this tissue look?
Trained against chronological age. These produce your intrinsic and extrinsic ages, and they are the foundation everything else is checked against.
Second generation
How old does this body behave?
Trained against aging phenotypes rather than the calendar, so they track health outcomes more closely than age alone. This is where methylation-based telomere length sits.
Third generation
How fast is this happening right now?
Measures rate rather than accumulated state. DunedinPACE answers whether you are currently aging faster or slower than one year per year, which is the number that responds soonest to a change in what you do.
Intrinsic versus extrinsic age
Blood carries many immune cell types and their proportions shift over time. Intrinsic age controls for that and reads the cells themselves. Extrinsic age includes it, so it reflects immune aging. Where the two diverge is itself informative, and the higher of the two is the one worth prioritizing.
Why the algorithms matter
The laboratory HFW uses offers all three generations of clocks, and the algorithms behind them are published and peer-reviewed. What they produce is an estimate. Estimates are useful precisely because they can be repeated and compared.
The output HFW finds most actionable is not the headline number. The same methylation data produces system-level estimates, which is how the report indicates that one system looks more strained than another. A single whole-body age is interesting. Knowing which systems appear to need support first is what changes what you do next.
Collection is a blood spot kit you complete at home. No lab visit is required.
The nine foundations, measured
HFW organizes longevity care around nine foundations. TruAge and TruHealth give us a read on each of them from a single blood spot, and the organ-system scoring indicates which are under the most strain. Open any one to see what it surfaces and what usually follows.
Glucose handling, insulin-resistance patterns and metabolic flexibility
Usually foundations first: nutrition, resistance training, sleep. Re-measure before adding anything on top.
Hormone-related methylation markers
Typically triggers confirmatory hormone testing rather than treatment. A signal is a reason to look properly, not to prescribe.
Inflammatory and immune-related patterns
Find what is driving it before considering anything that suppresses it.
Immune cell composition and extrinsic, or immune, age
Where immune aging looks advanced this shapes priorities and how often we re-measure.
Cellular energy and oxidative stress signals
Foundations first. Targeted support considered where the wider picture supports it.
Oxidative stress, membrane integrity and repair-related signals
Rarely acted on alone. Read alongside the systems above rather than treated as its own problem.
Inflammatory and immune patterns that often trace back to the gut
Usually prompts a GI-MAP before any gut protocol. Methylation cannot see the microbiome directly, so we look properly rather than assume.
Selected environmental exposure patterns
Reducing the exposure comes before supporting clearance.
Stress-related patterns, and pace of aging as a whole
Sleep, stress physiology and recovery. Frequently the highest-yield and least glamorous change on the list.
Often the answer is no new intervention at all. A finding that is stable, or that sits in a range you are already working on, is a reason to re-measure in six months rather than to add something to your plan.
When action is warranted, HFW draws on the full range: nutrition and diet, sleep and training, targeted supplementation, and hormone, peptide or GLP-1 therapy where it is clinically appropriate and lawfully available. Which of those applies is a clinical decision made with you, not a protocol that follows automatically from a score.
Advanced diagnostics
Not every patient needs every test. Your clinician selects from these based on your history, your goals and the specific question that needs answering. Open any of them to see what it reveals.
Biological age, pace of aging, epigenetic patterns, organ-system health, and major longevity risk signals
Metabolic health, inflammation, glucose, insulin, lipids, thyroid, hormones, liver, kidney, nutrients, cardiovascular risk, and safety markers
Nutrient processing, detox pathways, hormone metabolism, inflammation tendencies, cardiovascular patterns, cognitive risk, and personalized long-term strategy
Microbiome balance, dysbiosis, pathogens, inflammation, digestion, immune activity, and gut-barrier markers
Sex hormones, hormone metabolites, cortisol rhythm, adrenal patterns, melatonin, and hormone clearance
Nutrient deficiencies, oxidative stress, amino acids, mitochondrial markers, gut metabolites, and cellular energy patterns
Mitochondrial function, energy production, oxidative stress, neurotransmitter metabolites, B-vitamin patterns, yeast/bacterial patterns, and detox capacity
Cellular energy status and aging-related patterns that may guide mitochondrial and longevity support
Cortisol output, adrenal rhythm, stress physiology, sleep disruption, fatigue, immune modulation, and recovery patterns
Delayed immune reactivity patterns that may contribute to inflammation, GI symptoms, skin issues, fatigue, and energy crashes
A blood-based multi-cancer early detection test HFW can provide access to. It does not replace recommended cancer screening, and whether it is appropriate for you is a conversation to have with a clinician.
A targeted panel built around your symptoms, medications, health history, risks, protocol, and goals
A test earns its place when the result could change what happens next. More data is not automatically better care.
There is no membership to join first and nothing to commit to beyond the test itself. The free introductory call works out which one fits. Every price includes a 60 to 90 minute clinician review of your results. Longevity Membership members pay less on most testing. See member pricing →
Biological age, intrinsic and extrinsic, pace of aging, and organ and system-level scoring, with a clinician review of your report. The baseline everything else is measured against.
The test membership is built on and the one repeated each quarter, so the plan changes as your results do. Best when the question is what to correct first rather than how fast you are aging.
Best if you want the whole picture in a single sitting: everything in TruAge plus metabolic, nutrient, inflammatory, hormone-related, and exposure patterns, with one combined clinician review.
Best if you want everything connected and explained, with gut health included: three tests, integrated interpretation, and a dedicated Blueprint presentation of your prioritized roadmap. Conventional bloodwork and post-presentation follow-up are separate.
Depending on your testing, symptoms, safety markers, and goals, your plan may draw on biological age tracking, metabolic and hormone optimization, gut and digestive support, inflammation and immune regulation, nutritional repair, stress and sleep work, body composition and bone health, and a realistic nutrition and lifestyle strategy. Most people need a few of these, not all.
Peptides and bioregulators are optional tools inside that strategy, not the strategy. Neither is required for longevity care and neither replaces foundational work. When one is discussed, it is because there is a defined objective, the labs support it, and it belongs in your current plan. How HFW uses peptides →
Longevity is a trajectory, and a trajectory needs more than one point. Membership is for people ready to make a commitment to healthy aging, or to longer-term corrective care and health optimization: the testing, the clinician, and the coaching around your plan all year, retesting each quarter and adjusting as the results change. Not every plan has to be a membership; testing and focused care visits stand on their own.
Begins after a separate $450 initial TruHealth assessment, which includes a 60 to 90 minute clinician review. Bloodwork, medications, and treatments are purchased separately.
Book a Free ConsultationWhere people start
There is no membership to join before you begin and nothing to commit to beyond the test itself. You get results, a clinician reads them with you, and you decide what happens next from there.
TruAge
$500
Test and clinician review
Best if you want the aging picture, read properly by a clinician.
TruAge + TruHealth
$750
Both tests, one combined review
Best if you want the whole picture in a single sitting, rather than in pieces.
HFW Health Blueprint
$1,250
Three tests, integrated interpretation
Best if you want everything connected and explained, with gut health included.
What actually happens on the introductory call
It is a conversation, not a sales call. An advanced care clinician works through what is going on with you, what you have already tried, what you are hoping to change, and any results you already have.
You leave with a recommended starting point. In almost every case that is testing, and which of the three above makes sense depends on what you are trying to answer. If HFW is not the right fit for you right now, you will be told that too.
Your results are then reviewed with you over video, and that conversation is where any longer-term options, including membership, get discussed. Nothing about that is decided on the first call.
Schedule a Complimentary Introductory CallPrices shown are current as of the HFW pricing guide dated 16 August 2026 and include the clinician review noted for each. Conventional bloodwork and any additional specialty testing are separate. HSA and FSA cards are generally accepted, with eligibility determined by your plan.
Your personalized longevity plan
Built around your biology. Depending on your testing, symptoms, safety markers and goals, your plan may draw on any of these. Most people need a few of them, not all.
A strategy to identify what may be accelerating your aging patterns, then track whether your biomarkers, symptoms, and organ-system data improve over time.
Support for cellular stress, oxidative damage, membrane integrity, repair capacity, mitochondrial health, and tissue function.
Targeted support for cellular energy, fatigue patterns, oxidative stress, endurance, recovery, NAD+ status, and metabolic efficiency.
Support for thyroid, cortisol, estrogen, progesterone, testosterone, DHEA, insulin, and hormone metabolism when clinically appropriate.
A plan to improve glucose regulation, insulin response, lipids, liver markers, metabolic flexibility, body composition, and long-term cardiometabolic risk.
Targeted protocols to address dysbiosis, gut inflammation, poor digestion, immune activation, absorption issues, and gut-driven systemic dysfunction.
Support for chronic inflammation, immune resilience, autoimmune tendencies, poor recovery, pain patterns, and accelerated aging signals.
Professional-grade supplementation based on your nutrient deficiencies, absorption patterns, oxidative stress markers, and cellular needs.
A strategy to improve cortisol rhythm, nervous system regulation, sleep quality, recovery timing, cognitive function, and resilience.
When clinically appropriate, peptides may support recovery, tissue repair, metabolic function, mitochondrial health, gut integrity, immune signaling, cognitive support, and longevity-related goals.
Bioregulators may be considered for repair-related pathways, organ-specific resilience, immune support, circadian rhythm, vascular health.
A plan to protect lean mass, reduce visceral fat, support skeletal health, improve strength, and reduce age-related frailty risk.
A realistic plan built around blood sugar stability, protein needs, inflammation, gut health, hormone patterns, sleep, movement, stress, and your actual life.
Which of these applies is a clinical decision made with you. Nothing here follows automatically from a test result.
Advanced therapies in a broader strategy
Neither is required for longevity care, and neither replaces foundational work. When one is discussed, it is because there is a defined objective and a reason it belongs in your current plan.
Signal amplifiers
Cellular and organ-supportive regulators
Support specific biological signaling pathways
Areas of interest include repair-related pathways, protein synthesis, and tissue function
Recovery, metabolism, tissue repair, mitochondrial function, immune signaling, cognitive support, gut repair
Pineal, thymus, vascular, immune, circadian, and organ-system aging support
After reviewing labs, symptoms, risks, and foundational readiness
Often guided by biological age and organ-system data
Amplify the right signal at the right time
Build a more resilient cellular foundation
We review your symptoms, aging concerns, goals, and health history, then talk through whether HFW is the right fit.
TruAge and TruHealth testing establish your baseline. An advanced care clinician then interprets the results alongside your history, symptoms and goals, and builds a prioritized plan.
We find and address what's driving accelerated aging first, from gut and hormones to inflammation and nutrient gaps.
Your plan may include supplements, prescriptions, hormone support, and peptide or bioregulator pathways when clinically appropriate, with ongoing monitoring.
Quarterly labs, biological age reassessment, and symptom tracking help you protect your progress and keep the plan compounding as your biology changes.
What we monitor
Measurement continues after the first report. These are the things HFW watches to judge whether the areas you prioritized are moving in the intended direction, and whether the plan still makes sense.
Biological Age
Shows how your body may be aging beneath the surface
Pace of Aging
Helps evaluate whether your health trajectory is improving or accelerating
Organ-System Scores
Helps identify which systems need targeted support
Inflammatory Markers
Shows whether inflammation may be driving aging, pain, fatigue, or poor recovery
Glucose + Insulin
Tracks metabolic aging, blood sugar regulation, cravings, energy, and risk patterns
HbA1c + Lipids
Tracks long-term glucose patterns and cardiovascular risk
Mitochondrial Markers
Helps guide energy, fatigue, cellular resilience, and recovery strategies
NAD+ Status
May guide cellular energy and longevity-support protocols
Hormone Patterns
Shows how thyroid, cortisol, estrogen, progesterone, testosterone, DHEA, and insulin influence
Gut Markers
Identifies dysbiosis, inflammation, digestion, immune activity, and gut-barrier stress
Nutrient Status
Helps identify deficiencies limiting repair-related pathways, hormones, immunity, mood, and ene
Immune Markers
Helps evaluate immune resilience, inflammatory burden, and age-related immune stress
Body Composition
Tracks lean mass, fat mass, visceral fat, bone density, and sarcopenia risk
Sleep + Stress Rhythm
Helps track cortisol rhythm, nervous system load, recovery, and cognitive function
Symptoms
Energy, focus, sleep, mood, recovery, digestion, libido, pain, stamina, and resilience
Not every marker is re-checked every time. Cadence is a clinical decision based on what is actually changing.
Advanced care clinicians. Measurement-informed strategy. Long-term optimization.
25 years of clinical experience with a focus on hormones, gut health, chronic inflammation, women’s health, and care focused on underlying contributors.
Christina brings the whole-person lens to longevity care — connecting hormones, gut health, inflammation, nutrient status, stress patterns, and symptoms that standard visits often separate.
Dr. Eric Landi, KICP, DC
Over a decade of clinical experience with advanced functional testing, peptide therapy, metabolic optimization, and data-driven longevity protocols.
Dr. Landi helps guide HFW’s testing-first longevity strategy, peptide sequencing, mitochondrial optimization, bioregulator planning, and measurable outcome tracking.
Medical Director
20+ years in clinical practice with expertise in metabolic support, testosterone optimization, inflammation-related conditions, biological age tracking, and physician-level oversight.
Dr. Maslavi’s longevity philosophy centers on biomarker tracking, hormone and metabolic optimization, inflammation management, mitochondrial support, and proactive long-term care.
After getting my test results, Dr. Landi walked me through a number of helpful steps to restore my health. He is very knowledgeable and uses an in-depth functional medicine approach.
Stella Blanch ApoDr. Landi is highly knowledgeable and skilled in the field of functional medicine, but he also possesses a genuine empathy and compassion that is so often lacking in the traditional healthcare system.
Lauren GriffithClinician-led care with physician medical direction.
Christina Warner, APN-CBoard-Certified Women's Health Nurse Practitioner · Advanced care clinician
Dr. Eric Landi, KICP, DCCo-Founder · Longevity and Functional MedicineMedical direction: Dr. Saul Maslavi, MD, Board-Certified Family Medicine Physician
Meet the team →Book a free telehealth consultation to review your symptoms, history, longevity goals, and prior labs, and whether HFW's biological age tracking model is the right fit for you.
Book a Free ConsultationBased in Hillsdale, New Jersey. Care by telehealth.
Book a free virtual consultation to review your symptoms, health history, longevity goals, prior labs, and whether HFW’s biological age tracking model is the right fit for you.
Related reading
Clinician-reviewed guides on what these tests actually measure and how a result should be used.
Sixteen aging markers compared in the same 1,083 adults over 7.4 years, why they disagree by design, and what separates a result that changes your plan from a number that only sounds good.
What the published research and FDA's 2026 evaluation actually show, and seven questions that reveal the quality of a peptide plan.
Short answers to what people ask before booking.
Chronological age is how many years you have lived. Biological age is an estimate of how your body appears to be aging, based on measurable biological patterns rather than your birthday. Two people the same chronological age can show meaningfully different biological patterns. Biological age is an estimate and a piece of context, not a diagnosis and not a prediction of lifespan.
No one can promise that. Epigenetic testing estimates patterns associated with the pace and systems of aging, and a score can move. What a score change does not prove is that a person has literally reversed aging, that they will live longer, or that one specific treatment caused the change. HFW uses biological age as one layer of context alongside your history, conventional labs, body composition, and function, and does not guarantee age reversal.
TruAge is an epigenetic assessment that uses DNA methylation patterns and vendor algorithms to estimate aging-related patterns, pace of aging, and system or organ-level aging outputs. HFW uses it to add long-term context and to create a baseline that can be tracked alongside conventional risk factors, symptoms, function, and body composition. It is not a diagnosis.
TruAge is $500 standalone, covering the test and the clinician review together. TruAge combined with TruHealth is $750, covering both tests and the review. Longevity Membership members are entitled to additional discounts. TruAge is also included in the $1,250 Health Blueprint alongside TruHealth and GI-MAP.
Pace of aging is an estimate of how quickly biological aging patterns appear to be progressing, as opposed to a single point-in-time age estimate. It is one output among several and is interpreted alongside your symptoms, conventional labs, body composition, and function. It is context for prioritizing long-term care, not a verdict.
Some epigenetic reports estimate aging-related patterns for particular systems rather than one whole-body number. These estimates can help a clinician think about where to focus first. An elevated system-level estimate does not mean that organ has a disease, and it is interpreted alongside conventional evaluation.
TruAge estimates aging-related patterns using epigenetics. TruHealth is HFW’s advanced health assessment used to establish and monitor patterns across areas such as metabolic health, cellular and mitochondrial health, insulin resistance, nutrients, fatty acids, oxidative stress, immune and inflammatory patterns, hormone-related markers, and selected environmental exposures. TruAge tells you about pace and pattern of aging. TruHealth tells you what is currently happening that you may be able to act on. Many patients do both, which is why they are packaged together at $750.
No. It is an estimate of aging-related biological patterns, not a lifespan prediction. It also does not replace conventional risk assessment, guideline-recommended screening, or your physician’s evaluation.
HFW retests when the result can guide the next decision, not on a fixed marketing schedule. For members, biological age testing is an add-on rather than part of the quarterly TruHealth cycle. Your clinician will tell you what would need to change for a retest to be worth doing.
No. Peptides and bioregulators are optional tools inside a broader plan, not the plan itself. Most longevity strategies begin with measurement, then addressing meaningful dysfunction and foundations such as metabolic health, sleep, nutrition, training, and hormone patterns. An advanced therapy is considered only when there is a defined objective, appropriate evaluation, and a monitoring plan.
The introductory call is $0. A common longevity starting point is either the $450 initial TruHealth assessment or the $1,250 Health Blueprint, which combines TruAge, TruHealth, and GI-MAP with one integrated clinician presentation. Ongoing care through the Longevity Membership is $225 per month with an initial 12-month commitment, and the separate $450 initial TruHealth assessment is required before enrollment. Conventional bloodwork is billed separately by the laboratory.
The Health Blueprint is a $1,250 comprehensive assessment combining TruAge, TruHealth, and GI-MAP testing. An advanced care clinician reviews the results together, identifies your most important priorities, and presents a personalized roadmap in one integrated presentation. Conventional bloodwork is not included and is billed separately by the laboratory. Follow-up after the presentation is not included, and membership is not included. After the presentation you and the clinician discuss what makes sense next.
Have more questions? Ask Healie →
