Clinician-guided bioregulator support inside a broader longevity plan: biological age testing, eleven organ systems scored separately, 105+ epigenetic biomarkers, and bloodwork decide where support belongs, and a retest shows whether it is working. A small optional element, never the foundation.
Book a Free Consultation How it works ↓
100+ five-star reviewsClinician-ledTelehealthHSA/FSA acceptedAt HFW Longevity, we use clinician-supervised bioregulator therapy as part of a broader longevity framework — guided by biological age testing, organ-system data, advanced labs, symptoms, and long-term health goals.
Clinician-Led
100% Telehealth
Nationwide
HSA/FSA Accepted
24 pages on advanced testing, clinician-led protocols, and why strategy comes before any single compound.
Trusted by 1000+ patients across USA
Stella Blanch Apo
It’s been a blessing working with Dr. Landi and his entire team! After getting my test results, Dr. Landi walked me through a number of helpful steps to restore my health. He is very knowledgeable and uses an in-depth functional medicine approach in addressing health concerns. Bernadette is also very kind and thoughtful and I enjoy the interpersonal connection I have built with all of them.
Chase Natale
Fatimah Fahmy
Lauren Griffith
Kevin Heckman
You want longevity support, but you do not want to guess.
You want longevity support, and you do not want to guess.
Bioregulators are short peptide products, usually taken orally, associated with particular organs or systems and used to support cellular resilience rather than to stimulate it. The research is promising and still early, which is why HFW positions them carefully: no promises of age reversal, cancer prevention, organ regeneration, or a longer life. Organ-specific is a proposed framework, not an established clinical mechanism, and HFW does not claim a guaranteed organ-specific result.
Commercially, HFW treats current oral bioregulator products like retail supplements, not prescription therapies. If one is considered at all, your clinician explains the objective, the limitations, how it fits the broader plan, and when it will be reassessed. The foundations of sleep, nutrition, training, metabolic health, and appropriate correction come first.
Bioregulators are not meant to be stacked forever or used blindly. Any use is individual, defined by objective, and reassessed.
A free telehealth call with an advanced care clinician to review where you are, what you have already tried, and whether bioregulator support belongs in your plan at all. Often the more useful first step is testing, or correcting something more basic.
Biological age, pace of aging, and organ-system data may help guide where support should be focused, alongside bloodwork for inflammation, nutrients, hormones, and metabolic and safety markers. See the testing →
Sleep, nutrition, training, metabolic health, gut function, and nutrient status are addressed first or alongside. Many patients begin with broader resilience work before anything more targeted is considered.
If a bioregulator is selected, it is chosen for a specific objective, sequenced with the rest of your plan, and given a point at which labs, symptoms, tolerance, and progress decide whether it continues, changes, pauses, or stops. HFW does not publish protocols, cycles, or product lists, because there is no universal schedule.
Members repeat TruHealth roughly every quarter with a scheduled clinician review, so the plan follows your results rather than a product menu. See membership →
Most bioregulator plans never look at these. When clinically relevant, HFW does.
Hormone patterns, vascular health, and metabolic health are part of the picture too. Cellular support works best when energy production and inflammation are understood.
24 pages on advanced testing, clinician-led protocols, and why strategy comes before any single compound.
HEAL FROM WITHIN
Ideal for patients focused on foundational health, hormone balance, and preventive care.
Ideal for patients seeking a deeper root-cause approach and functional medicine solutions.
Ideal for patients focused on foundational health, hormone balance, and preventive care.
| Typical Longevity Care | HFW Longevity | |
|---|---|---|
What they look at |
Symptoms, age, and general anti-aging goals
|
Biological age, organ-system health, cellular stress, inflammation, immune resilience, vascular health, hormones, gut, metabolism, and recovery
|
What you hear |
“This is good for anti-aging.”
|
“Let’s see where your body is aging, stressed, or under-supported.”
|
Testing |
Often minimal or skipped
|
TruAge + TruHealth, comprehensive bloodwork, functional testing, hormone, gut, nutrient, mitochondrial, and inflammation markers when appropriate
|
Treatment |
Generic longevity stack or product menu
|
Organ-specific bioregulator strategy with clinical sequencing and monitoring
|
Support |
Little follow-up after purchase
|
Quarterly labs, regular reviews, symptom tracking, and protocol adjustments
|
Goal |
General anti-aging support
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Cellular resilience, organ support, biological age tracking, and long-term healthspan
|
Access |
DIY, supplement-style, or one-time order
|
100% telehealth with clinician-supervised care and at-home or local testing options
|
What you hear
Bioregulators are not meant to be used blindly. Your cellular strategy should match your biology.
| What We Evaluate | Why It Matters |
|---|---|
|
Biological Age
|
Your birthday tells one story. Biological age testing helps show how your body may be aging beneath the surface.
|
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Organ-System Health
|
TruHealth-style organ data may help identify which systems appear older, stressed, or under-supported.
|
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Cellular Resilience
|
Cellular stress, oxidative damage, nutrient status, and repair capacity affect how well your body responds to any therapy.
|
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Mitochondrial Function
|
Mitochondria drive energy, recovery, metabolism, and resilience. Cellular therapy works best when energy production is understood.
|
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Immune Function
|
Immune aging and poor immune resilience may affect inflammation, recovery, reactivity, and long-term healthspan.
|
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Vascular Health
|
Blood vessel function influences circulation, cardiovascular aging, recovery, cognition, and tissue support.
|
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Circadian Rhythm
|
Sleep rhythm, cortisol patterns, melatonin signaling, and recovery cycles affect repair and biological aging.
|
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Inflammation
|
Chronic inflammation can interfere with repair, hormone signaling, immunity, metabolism, and cellular function.
|
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Hormonal Health
|
Thyroid, cortisol, estrogen, progesterone, testosterone, insulin, and DHEA all influence aging, recovery, and resilience.
|
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Gut Health
|
Gut dysfunction can drive inflammation, immune activation, poor absorption, brain fog, and poor treatment response.
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Nutrient Status
|
Nutrient deficiencies can limit cellular repair, energy production, detoxification, immune function, and hormone signaling.
|
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Metabolic Health
|
Glucose, insulin, lipids, body composition, and metabolic flexibility influence aging speed and long-term risk.
|
Your birthday tells one story. Biological age testing helps show how your body may be aging beneath the surface.
TruHealth-style organ data may help identify which systems appear older, stressed, or under-supported.
Cellular stress, oxidative damage, nutrient status, and repair capacity affect how well your body responds to any therapy.
Mitochondria drive energy, recovery, metabolism, and resilience. Cellular therapy works best when energy production is understood.
Immune aging and poor immune resilience may affect inflammation, recovery, reactivity, and long-term healthspan.
Blood vessel function influences circulation, cardiovascular aging, recovery, cognition, and tissue support.
Sleep rhythm, cortisol patterns, melatonin signaling, and recovery cycles affect repair and biological aging.
Chronic inflammation can interfere with repair, hormone signaling, immunity, metabolism, and cellular function.
Thyroid, cortisol, estrogen, progesterone, testosterone, insulin, and DHEA all influence aging, recovery, and resilience.
Gut dysfunction can drive inflammation, immune activation, poor absorption, brain fog, and poor treatment response.
Nutrient deficiencies can limit cellular repair, energy production, detoxification, immune function, and hormone signaling.
Glucose, insulin, lipids, body composition, and metabolic flexibility influence aging speed and long-term risk.
| Peptides | Bioregulators | |
|---|---|---|
|
How we think about them
|
Signal amplifiers
|
Cellular and organ-supportive regulators
|
|
Primary role
|
Support specific biological signaling pathways |
Support cellular repair, protein synthesis, and organ-specific resilience
|
|
Common focus areas
|
Recovery, metabolism, tissue repair, mitochondrial function, immune signaling, cognitive support, gut repair
|
Pineal, thymus, vascular, immune, circadian, and organ-system aging support
|
|
How HFW uses them
|
Strategically, based on testing and goals
|
Often guided by biological age and organ-system health data
|
|
Clinical philosophy
|
Amplify the right signal at the right time
|
Build a more resilient system before pushing performance
|
Signal amplifiers
Support specific biological signaling pathways
Recovery, metabolism, tissue repair, mitochondrial function, immune signaling, cognitive support, gut repair
Strategically, based on testing and goals
Amplify the right signal at the right time
Cellular and organ-supportive regulators
Support cellular repair, protein synthesis, and organ-specific resilience
Pineal, thymus, vascular, immune, circadian, and organ-system aging support
Often guided by biological age and organ-system health data
Build a more resilient system before pushing performance
| Test | What It Can Reveal |
|---|---|
|
TruAge + TruHealth Testing
|
Biological age, pace of aging, and organ-system health across immune, metabolic, hormonal, cardiovascular, and other systems
|
|
Comprehensive Bloodwork
|
CBC, CMP, glucose, insulin, HbA1c, lipids, kidney markers, liver markers, thyroid patterns, inflammation, hormones, and safety markers
|
|
Custom Longevity Blood Panel
|
A targeted panel built around your symptoms, goals, medications, health history, and the bioregulator pathway being considered
|
|
Organic Acids Test / Metabolic Testing
|
Mitochondrial function, energy production, oxidative stress, neurotransmitter metabolites, B-vitamin patterns, and metabolic byproducts
|
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Metabolomix+ Nutritional Panel
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Nutrient deficiencies, oxidative stress, amino acids, mitochondrial markers, gut metabolites, and cellular energy patterns
|
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NAD+ Level Testing
|
Cellular energy status and aging-related patterns that may guide mitochondrial and longevity support
|
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DUTCH Complete Hormone Test
|
Sex hormones, hormone metabolites, cortisol rhythm, adrenal patterns, and hormone clearance
|
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GI-MAP Stool Analysis
|
Gut dysbiosis, pathogens, inflammation, digestion, immune activity, and gut barrier markers
|
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Genetic Testing When Appropriate
|
Nutrient processing, detox pathways, inflammation tendencies, hormone metabolism, and long-term personalization strategy
|
Biological age, pace of aging, and organ-system health across immune, metabolic, hormonal, cardiovascular, and other systems
CBC, CMP, glucose, insulin, HbA1c, lipids, kidney markers, liver markers, thyroid patterns, inflammation, hormones, and safety markers
A targeted panel built around your symptoms, goals, medications, health history, and the bioregulator pathway being considered
Mitochondrial function, energy production, oxidative stress, neurotransmitter metabolites, B-vitamin patterns, and metabolic byproducts
Nutrient deficiencies, oxidative stress, amino acids, mitochondrial markers, gut metabolites, and cellular energy patterns
Cellular energy status and aging-related patterns that may guide mitochondrial and longevity support
Sex hormones, hormone metabolites, cortisol rhythm, adrenal patterns, and hormone clearance
Gut dysbiosis, pathogens, inflammation, digestion, immune activity, and gut barrier markers
Nutrient processing, detox pathways, inflammation tendencies, hormone metabolism, and long-term personalization strategy
Peptides and bioregulators are different tools. Therapeutic peptides are signal amplifiers: they support specific biological signaling pathways and are used strategically, based on testing and goals, for recovery, metabolism, tissue repair, mitochondrial function, immune signaling, and gut repair. Bioregulators are cellular and organ-supportive regulators, generally shorter, typically taken orally, and discussed in terms of organ or tissue association rather than a single defined mechanism. Their evidence base is considerably less developed.
HFW's philosophy for both: build a more resilient system before pushing performance, and amplify the right signal at the right time. Neither is required for longevity care, and neither replaces foundational work.
How HFW uses peptides →Bioregulators are retail products, priced individually and purchased separately. They are not included in the Longevity Membership or the Functional Medicine Corrective Program, and they do not receive the 15% member discount that applies to eligible peptide protocol packages, TRT, and HRT.
What is worth paying for first is the measurement that decides whether they belong in your plan: TruHealth is $450, TruAge is $500, and TruAge with TruHealth is $750, each including a 60 to 90 minute clinician review of your results. Longevity Membership members pay less on most testing (see member pricing →). Nothing about a bioregulator is decided from a website.
Compare the tests →Bioregulators are optional. The measured plan around them is the point. Membership is for people ready to make a commitment to healthy aging, or to longer-term corrective care and health optimization: the testing, the clinician, and the coaching around your plan all year, retesting each quarter and adjusting as the results change. Not every plan has to be a membership; testing and focused care visits stand on their own.
Begins after a separate $450 initial TruHealth assessment, which includes a 60 to 90 minute clinician review. Bloodwork, medications, and treatments are purchased separately.
Book a Free ConsultationBuilt around your biology. Depending on your testing, symptoms, safety markers, and goals, your plan may include.
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Bioregulators are not meant to be stacked forever. They are selected, sequenced, pulsed, tracked, and adjusted.
| Protocol Element | What It Means |
|---|---|
|
Clinical Fit Review
|
We determine whether bioregulator therapy fits your history, symptoms, labs, goals, and current health foundation.
|
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Biological Age Guidance
|
TruAge and organ-system data may help guide where support should be focused.
|
|
Foundational First
|
Many patients begin with broader cellular resilience before moving into more targeted optimization.
|
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30-Day Protocols
|
Some patients may begin with an initial structured protocol to establish a foundation.
|
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10-Day Pulses
|
Certain protocols may shift into short monthly pulses depending on goals and response.
|
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Quarterly Pulses
|
Some patients may use bioregulator support around quarterly optimization cycles.
|
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Alternating-Month Pulses
|
More advanced strategies may alternate support based on severity, goals, budget, and clinical priorities.
|
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Ongoing Review
|
Labs, symptoms, tolerance, and progress determine whether the plan continues, changes, pauses, or advances.
|
We determine whether bioregulator therapy fits your history, symptoms, labs, goals, and current health foundation.
TruAge and organ-system data may help guide where support should be focused.
Many patients begin with broader cellular resilience before moving into more targeted optimization.
Some patients may begin with an initial structured protocol to establish a foundation.
Certain protocols may shift into short monthly pulses depending on goals and response.
Some patients may use bioregulator support around quarterly optimization cycles.
More advanced strategies may alternate support based on severity, goals, budget, and clinical priorities.
Labs, symptoms, tolerance, and progress determine whether the plan continues, changes, pauses, or advances.
We review your symptoms, longevity goals, recovery, and health history, then talk through whether HFW is the right fit.
Biological age testing and advanced labs show where your body is aging and which systems need support. Kits ship to your door or get coordinated locally.
Your provider reviews your aging data and builds a personalized cellular resilience strategy with clear priorities.
We build the foundation first, addressing gut, hormones, inflammation, and nutrient gaps, so your cells can actually respond to therapy.
Your protocol begins with clinician-supervised bioregulator sequencing and pulse strategies, supplement support, and ongoing monitoring.
Quarterly labs, biological age reassessment, and response tracking help you protect your progress and adjust the plan as your biology changes.
Bioregulator therapy is not a 30-day anti-aging hack. It is a cellular resilience process.
| Quarter | Focus | What This Means for Bioregulator Therapy |
|---|---|---|
|
Q1: Discover & Correct
|
Find the root. Build the foundation.
|
Biological age testing, organ-system review, safety labs, inflammation and mitochondrial assessment, first-stage correction
|
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Q2: Activate & Improve
|
Build momentum. Feel the shift.
|
Initial or pulsed bioregulator strategy, tolerance review, sleep, energy, immune, recovery, and symptom trend tracking
|
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Q3: Optimize & Perform
|
Improve systems. Elevate resilience.
|
Organ-specific refinement, mitochondrial and peptide sequencing, vascular or immune support, advanced therapy consideration
|
|
Q4: Sustain & Thrive
|
Protect progress. Build longevity.
|
Maintenance pulses, biological age reassessment, long-term healthspan planning, prevention strategy, relapse prevention
|
Q1
Find the root. Build the foundation.
Q2
Activate & Improve
Build momentum. Feel the shift.
Q3
Improve systems. Elevate resilience.
Q4
Protect progress. Build longevity.
| We Track | Why It Matters |
|---|---|
|
Biological Age
|
Shows whether your body may be aging faster or slower than your chronological age
|
|
Pace of Aging
|
Helps evaluate whether your health trajectory is moving in the right direction
|
|
Organ-System Scores
|
Helps identify which systems may need targeted support
|
|
Safety Bloodwork
|
Helps determine whether therapy remains appropriate as your plan continues
|
|
Inflammatory Markers
|
Shows whether inflammation may be interfering with repair and resilience
|
|
Immune Markers
|
Helps evaluate immune stress, immune resilience, and inflammatory burden
|
|
Vascular Markers
|
Supports cardiovascular and blood-vessel-related longevity strategy
|
|
Mitochondrial Markers
|
Helps guide cellular energy, fatigue, recovery, and oxidative stress support
|
|
NAD+ Status
|
May help guide cellular energy and longevity-focused protocols
|
|
Hormone Patterns
|
Shows how thyroid, cortisol, estrogen, progesterone, testosterone, DHEA, and insulin may influence aging
|
|
Gut Markers
|
Identifies dysbiosis, inflammation, digestion, immune activity, and barrier-related concerns
|
|
Nutrient Status
|
Helps determine whether deficiencies are limiting cellular repair or recovery
|
|
Sleep + Circadian Rhythm
|
Helps track recovery timing, cortisol rhythm, melatonin patterns, and nervous system load
|
|
Body Composition
|
Helps track lean mass, fat mass, visceral fat, bone health, and metabolic resilience
|
|
Symptoms
|
Energy, mood, sleep, focus, recovery, immune resilience, pain, digestion, libido, and stamina
|
|
Tolerance + Response
|
Ensures the protocol is adjusted or stopped when your body signals a problem
|
Shows whether your body may be aging faster or slower than your chronological age
Helps evaluate whether your health trajectory is moving in the right direction
Helps identify which systems may need targeted support
Helps determine whether therapy remains appropriate as your plan continues
Shows whether inflammation may be interfering with repair and resilience
Helps evaluate immune stress, immune resilience, and inflammatory burden
Supports cardiovascular and blood-vessel-related longevity strategy
Helps guide cellular energy, fatigue, recovery, and oxidative stress support
May help guide cellular energy and longevity-focused protocols
Shows how thyroid, cortisol, estrogen, progesterone, testosterone, DHEA, and insulin may influence aging
Identifies dysbiosis, inflammation, digestion, immune activity, and barrier-related concerns
Helps determine whether deficiencies are limiting cellular repair or recovery
Helps track recovery timing, cortisol rhythm, melatonin patterns, and nervous system load
Helps track lean mass, fat mass, visceral fat, bone health, and metabolic resilience
Energy, mood, sleep, focus, recovery, immune resilience, pain, digestion, libido, and stamina
Ensures the protocol is adjusted or stopped when your body signals a problem
Most patients work with us through a structured longevity membership model that includes:
Clinician-led care. Root-cause strategy. Long-term optimization
Dr. Eric Landi, KICP, DC
Over a decade of clinical experience with advanced functional testing, peptide therapy, metabolic optimization, and data-driven longevity protocols.
Medical Director
Real progress. Real support. No shame.
Stella Blanch Apo
It’s been a blessing working with Dr. Landi and his entire team! After getting my test results, Dr. Landi walked me through a number of helpful steps to restore my health. He is very knowledgeable and uses an in-depth functional medicine approach in addressing health concerns. Bernadette is also very kind and thoughtful and I enjoy the interpersonal connection I have built with all of them.
Chase Natale
Fatimah Fahmy
I have been working with Dr Landi for several months now. He is extremely knowledgeable, attentive and responsive. He actually listens which is rare in medicine these days. I’m excited to see what the results are from my protocol in a couple of months. Highly recommend his practice if you’re looking into functional medicine.
Lauren Griffith
Dr. Landi is highly knowledgeable and skilled in the field of functional medicine, but he also possesses a genuine empathy and compassion that is so often lacking in the traditional healthcare system. Dr. Landi connects to each of his patients on a personal level, works with you every step of the way, and makes you feel supported while navigating challenging health obstacles.
Kevin Heckman
I found out about the practice of Functional Dr’e last year and realized this is what I need! Finding Dr Landi so close to home was awesome. We appreciated his candor, knowledge and engaging personality. He exuded caring and interest in me and my situation. I feel he had repeatedly gone the extra mile for me so our collaboration is successful.
After getting my test results, Dr. Landi walked me through a number of helpful steps to restore my health. He is very knowledgeable and uses an in-depth functional medicine approach.
Stella Blanch ApoWe appreciated his candor, knowledge and engaging personality. He exuded caring and interest in me and my situation. I feel he had repeatedly gone the extra mile for me so our collaboration is successful.
Kevin HeckmanClinician-led care with physician medical direction.
Christina Warner, APN-CBoard-Certified Women's Health Nurse Practitioner · Advanced care clinician
Dr. Eric Landi, KICP, DCCo-Founder · Longevity and Functional MedicineMedical direction: Dr. Saul Maslavi, MD, Board-Certified Family Medicine Physician
Meet the team →Book a free telehealth consultation to talk through where your body may be aging, stressed, or under-supported, what is worth measuring, and whether bioregulator support belongs in your plan.
Book a Free ConsultationBased in Hillsdale, New Jersey. Care by telehealth.
Book a free virtual consultation to review your symptoms, longevity goals, health history, prior labs, and whether clinician-supervised bioregulator therapy belongs in your long-term optimization plan.
Short answers to what people ask before booking.
Bioregulators are an emerging class of short peptide products associated with particular organs or systems. Some research is promising, but the evidence is not strong enough to promise age reversal, cancer prevention, organ regeneration, or a longer life. HFW treats current oral bioregulator products commercially like retail supplements.
They are generally shorter, are typically taken orally rather than injected, and are commonly discussed in terms of organ or tissue association rather than a single defined mechanism. Commercially, HFW treats current oral bioregulator products like retail supplements rather than as prescription therapies. The evidence base is different too, and it is considerably less developed than for the better-studied therapeutic peptides.
It refers to the theory that a given short peptide is associated with a particular tissue or system. It is a proposed framework, not an established clinical mechanism, and it should not be read as a promise of an organ-specific effect. HFW does not claim a guaranteed organ-specific result.
No. There is no product that reverses aging, and HFW does not make that claim. Bioregulators may be considered as one small optional element inside a broader plan with a defined objective and a reassessment point, but they are not an anti-aging solution.
No. HFW does not claim that bioregulators regenerate organs, prevent cancer, extend lifespan, repair DNA, or restore telomeres in a way that proves better health. Any source telling you otherwise is going beyond what the evidence supports.
There is a body of research associated with this class, much of it older and much of it from a specific research lineage, and it needs to be read with careful attention to study design, size, and endpoint. Some of it is genuinely interesting. None of it supports the marketing claims commonly made online. HFW’s position is that the evidence is not strong enough to promise a clinical outcome.
HFW treats current oral bioregulator products commercially like retail supplements, and supplements are not FDA approved as drugs. As with any product, appropriateness depends on the individual, their history, and their other medications. HFW does not claim any product is without risk or is appropriate for everyone.
No. If a bioregulator is considered at all, HFW explains the objective, the limitations, how it fits the broader plan, and when it will be reassessed. It is a small optional element, never a foundation, and the foundations of sleep, nutrition, training, metabolic health, and appropriate correction come first.
No. Retail bioregulators are not included in membership and do not receive the 15% member or Functional Medicine Corrective Program discount. Members and program patients pay regular retail pricing for supplements outside the periods expressly included in their programs.
No. There is no universal rotation schedule, and HFW does not publish protocols, cycles, or product lists. Any use is individual, defined by objective, and reassessed.
Have more questions? Ask Healie →
